Parameter Patients Controls p Value

Hypercholesterolemia 31% 16% 0.016
Myocardial infarct 3% 0% 0.22
Any cardiovascular 39% 21% 0.005
Other cancers 15% 6% 0.048
Deafness/hearing 14% 5% 0.04
Autonomic neuropathy 7.7% 1.5% 0.1
Peripheral neuropathy 10.4% 4.5% 0.17
Anemia 5.7% 1.4% 0.22
Osteoporosis 2.4% 0 0.3

(Demographic characteristics well balanced)