Median PFS (mos)

HR p-value Objective Tumor Response (CR+PR+SD)

p-value
Pem Placebo Pem Placebo

All patients 4.3 2.6 0.502 <0.00001 51.7 33.3 <0.001
Non-squamous (n=482) 4.5 2.6 0.444 <0.00001 57.7 32.7 <0.001
Adenocarcinoma (n=329) 4.7 2.6 0.452 <0.00001 61.0 33.0 <0.001
Large Cell (n=20) 3.5 2.1 0.400 0.109 45.5 33.3 0.670
Other (n=133) 4.2 2.8 0.433 0.0002 51.1 31.7 0.041
Squamous (n=181) 2.8 2.6 0.692 0.039 34.8 34.8 1.000