Journal of Clinical Oncology, ASCO Annual Meeting Proceedings (Post-Meeting Edition).
Vol , No 18S ( Supplement), :
© 2009 American Society of Clinical Oncology

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Med OS and PFS by ARM w/ or w/o Dose Reduction

Arm A Arm C No Reduction (n=106) Reduction (n=134) No Reduction (n=128) Reduction (n=77) OS (mos) 12.9 13.6 9.2 10.1 PFS (mos) 7.3 7.4 2.0 3.6

Hazard Ratios for Reduction versus No Reduction (HR < 1 favors dose reduction) Arm A Arm C HR P HR P OS .82 .17 .85 .30 PFS .81 .14 .65 .0070

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